6/1/2023 0 Comments Alpus liqudations![]() nepalensis is prescribed to treat diarrhea and paste from the leaves is applied on cuts and wounds as a hemostatic. nepalensis are used in dysentery, stomach ache, and diarrhea in Indian system of medicine (Ayurveda). The bark of Alnus glutinosa is alterative, astringent, cathartic, febrifuge, tonic, and useful in mouth and throat inflammations, the vinegar extract of inner bark of plant produces a useful wash to treat lice and a range of skin problems such as scabies and scabs. Alnus japonica is a popular folk medicine in Korea for cancer and hepatitis. These have been used for the treatment of various diseases including cancer and as an alterative, astringent, cathartic, emetic, febrifuge, galactogogue, hemostatic, parasiticide, skin tonic, vermifuge, etc. The members of genus Alnus are well known for their traditional medicinal values. ![]() The aim of the present review is to summarize the various researches related to the chemistry and pharmacology of genus Alnus. ![]() The members of genus Alnus are well known for their traditional uses in the treatment of various diseases like cancer, hepatitis, inflammation of uterus, uterine cancer, rheumatism, dysentery, stomachache, diarrhea, fever, etc. Some ellagitannines showed hepatoprotective activity even in a dose of 1 mg/kg which is ten-fold smaller compared with the dose of traditional flavonoid-based drugs. Diarylheptanoids are the dominant constituents within the genus Alnus, few of them exhibited antioxidant effects and inhibitory activity against nuclear factor kappaB activation, nitric oxide and tumor necrosis factor-α production, human umbilical vein endothelial cells, farnesyl protein transferase, cell-mediated low-density lipoprotein oxidation, HIF-1 in AGS cells, and the HIV-1-induced cytopathic effect in MT-4 cells. The plants of this genus contain terpenoids, flavonoids, diarylheptanoids, phenols, steroids, and tannins. The genus Alnus has been reviewed for its chemical constituents and biological activities including traditional importance of some common species.
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